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There is an emerging consensus that situations of acute or chronic imbalance between the antioxidative capacity of cells and tissues, and the production of pro oxidative species, is associated with the development of a number of human diseases

Differences in TMAO area under the curve (AUC) were analyzed using linear mixed-effects models

Ex-4 can penetrate deep into the limbic system [66,67], well-known for its role in drug addiction due to changes in synaptic plasticity [103]

Thiazolidinediones (pioglitazone): Often cause significant weight gain plus fluid retention

These effects are mainly attributed to the activation of Nrf2

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